HTS Tools

High Throughput Screening tools for the scientist interested in analyzing large datasets. <p>The goal of this work is to get the science back into the hands of the scientists by providing some simplified solutions to some difficult problems in High Throughput Screening (HTS) analysis. Solutions that avoid the added complexity, reduced ease of use and hiding of functionality that can make n-tiered solutions frustrating to work with. If you like looking at all the numbers generated in an experiment on your desktop with current powerful analytical tools. Welcome! You have found the right place! The computer is indispensable in the field of drug discovery and HTS. The problem is... dealing with the complexity of the present day analytical models. There is no doubt that these current models offer potential solutions to once difficult or impossible problems in analysis. The question is, are they accessible for solving problems in a simplistic fashion in HTS? Is the learning curve low enough to allow the most novice scientist the ability to solve problems of great magnitude and significance with only a desktop workstation? The work posted here is an effort to provide tools for allowing scientists at the desktop to take advantage of the modern application models in a simplistic and productive fashion. The tools provide solutions to common problems in HTS using some popular and powerful applications on a desktop PC. Fantastic for minimizing analysis times for some difficult processes in HTS! Presented free for download are a number of tools for the scientist interested in HTS and assay development. What is here? Add-ins for the PC versions of Microsoft Excel and Access editions 2000 and 2002! These add-ins provide additional functionality on top of what is already present in these application models that is specific to HTS. Data retrieval, statistics, percent of control, plate map reporting, sample data generation, logical models, etc. are all addressed here! If you love science and HTS check these programs out. Perfection? While the add-ins provide some fantastic functionality there are some imperfections to be aware of. The Excel add-in does not have an inherently tight programmatic flow to it but offers some nice functionality. The code base for this add-in is open so you are welcome to see how things work and make changes if you so like. It was originally designed to show the how and why you would want to work with data in columns (relational concepts) and not in Excel. It ended up showcasing some nice features of Excel but it still has some spreadsheet problems associated with it (I can put anything anywhere!). The functionality present in the Access add-ins are programmatically implemented in a tighter fashion than the equivalent functionality in the Excel add-in. The Access add-ins also handle basic user generated errors in a more responsible fashion. The code base, in all the Access add-ins, are closed (compiled into mde files). More time was spent putting the Access add-ins together and the programmatic flow is consistent and fluid. All of the work presented here is the product of our hard work. Please be respectful of this. The work here is free for distribution but not for post download sale. All rights of design, concept and implementation of the work presented on these pages are reserved by the authors so noted. C. Eric Cashon cecashon@aol.com <p align="center"> <a href="http://www.htstools.com/contents.html">contents</a>